17-year-old Ichirou Satou is an average guy who always happens to find himself in a perverted situation with his teacher, Kana Kojima. Follow this erotic love comedy about their mishaps and how Ichirou and Kana choose to handle them.

The four Golden Times one-shot prequels are included formally as Chapters 1-4 of Nande koko ni sensei ga!? in the Volume 01 Tankobon. The series continuation begins at Chapter 5. Later chapters and volumes follow new student-teacher couples at the same school Ichirou and Kana attend.